Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 6/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767058 | 1.00 | FEN1 (0.38) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766788 | 0.91 | FEN1 (0.39) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766046 | 0.91 | FEN1 (0.39) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766005 | 0.91 | FEN1 (0.35) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766976 | 0.91 | FEN1 (0.35) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12736270 | 0.90 | FEN1 (0.38) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12740826 | 0.90 | FEN1 (0.38) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14767171 | 0.90 | GABRA1 (0.35) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766075 | 0.90 | GABRA1 (0.35) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14766616 | 0.89 | FEN1 (0.35) | FEN1ALOX5APSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |