SCHEMBL14765815

SCHEMBL14765815

CCCCOc1ccc(C2CCC(OCc3ccc(C4CCC(OCCC)CC4)c(F)c3F)CC2)cc1F

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.36
KDM1A O60341 2/20 0.35
SCN9A Q15858 1/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
HTR1A P08908 1/20 0.30
PPARG P37231 2/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766128 0.97 KDM1A (0.36) NAAAKDM1ASCN9APDE4APDE4B
SCHEMBL14765883 0.94 KDM1A (0.40) NAAAKDM1ASCN9APDE4APDE4B
SCHEMBL12736642 0.93 NAAA (0.35) NAAAKDM1ASCN9APDE4APDE4B
SCHEMBL14765779 0.93 KDM1A (0.40) KDM1ASCN9APDE4APDE4BPDE4C
SCHEMBL14766226 0.91 NAAA (0.33) NAAAKDM1ASCN9APDE4APDE4B
SCHEMBL12736644 0.91 NAAA (0.35) NAAAKDM1ASCN9APDE4APDE4B
SCHEMBL14766554 0.90 SCN9A (0.33) NAAAKDM1ASCN9A
SCHEMBL14766615 0.90 SCN9A (0.34) NAAASCN9AHTR1A
SCHEMBL14765674 0.90 KDM1A (0.41) KDM1ASCN9APDE4APDE4BPDE4C
SCHEMBL14765897 0.90 SCN9A (0.34) NAAASCN9AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed