Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766672 | 0.94 | ALOX5AP (0.32) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14765842 | 0.94 | ALOX5AP (0.32) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14765863 | 0.94 | GABRA1 (0.33) | CNR2GABRA1GABRB2MAPTL3MBTL1 | |
| SCHEMBL14767102 | 0.92 | GABRA1 (0.33) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14765952 | 0.92 | GABRA1 (0.33) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14765994 | 0.91 | ALOX5AP (0.33) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14767182 | 0.91 | ALOX5AP (0.33) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14766325 | 0.90 | CNR2 (0.32) | CNR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14767075 | 0.90 | SCN9A (0.34) | SCN9ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL14765693 | 0.90 | CNR2 (0.30) | CNR2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |