Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766053 | 0.96 | S1PR1 (0.45) | S1PR1S1PR3RARBCNR2PTPN11 | |
| SCHEMBL14767087 | 0.95 | S1PR1 (0.43) | S1PR1S1PR3RARBCNR2PTPN11 | |
| SCHEMBL14765764 | 0.94 | S1PR1 (0.39) | S1PR1S1PR3RARBCNR2FFAR1 | |
| SCHEMBL14765851 | 0.92 | S1PR1 (0.51) | S1PR1S1PR3RARBCNR2PTPN11 | |
| SCHEMBL12735729 | 0.91 | FFAR1 (0.38) | S1PR1S1PR3FFAR1FFAR4CYP2C9 | |
| SCHEMBL14766811 | 0.91 | S1PR1 (0.43) | S1PR1S1PR3RARBCNR2PTPN11 | |
| SCHEMBL14766030 | 0.90 | S1PR1 (0.49) | S1PR1S1PR3RARBCNR2PTPN11 | |
| SCHEMBL14766470 | 0.89 | CNR2 (0.42) | S1PR1S1PR3CNR2CNR1MEN1 | |
| SCHEMBL14766286 | 0.89 | CNR2 (0.42) | S1PR1S1PR3CNR2CNR1MEN1 | |
| SCHEMBL14766770 | 0.89 | FFAR1 (0.41) | S1PR1S1PR3CNR2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |