Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765764 | 0.95 | S1PR1 (0.39) | FFAR1FFAR4S1PR1S1PR3GPR84 | |
| SCHEMBL14767087 | 0.94 | S1PR1 (0.43) | FFAR1FFAR4S1PR1S1PR3C3AR1 | |
| SCHEMBL14766811 | 0.92 | S1PR1 (0.43) | FFAR1FFAR4S1PR1S1PR3C3AR1 | |
| SCHEMBL12740185 | 0.90 | FFAR1 (0.40) | FFAR1FFAR4S1PR1S1PR3 | |
| SCHEMBL14767167 | 0.89 | FFAR1 (0.42) | FFAR1FFAR4PPARDKDM4ENPC1 | |
| SCHEMBL14766658 | 0.89 | MAOB (0.39) | FFAR1FFAR4S1PR1S1PR3GPR84 | |
| SCHEMBL14766910 | 0.89 | FFAR1 (0.43) | FFAR1FFAR4S1PR1S1PR3GPR84 | |
| SCHEMBL14765871 | 0.89 | S1PR1 (0.45) | FFAR1FFAR4S1PR1S1PR3C3AR1 | |
| SCHEMBL14766896 | 0.88 | FFAR1 (0.47) | FFAR1FFAR4S1PR1S1PR3C3AR1 | |
| SCHEMBL14766597 | 0.87 | CNR2 (0.36) | FFAR1FFAR4GPR84CNR2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |