Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765960 | 0.98 | S1PR1 (0.38) | S1PR1S1PR3FFAR4GABRA1GABRB2 | |
| SCHEMBL14766875 | 0.94 | FFAR4 (0.36) | S1PR1S1PR3FFAR4GABRA1GABRB2 | |
| SCHEMBL14765993 | 0.94 | S1PR1 (0.42) | S1PR1S1PR3FFAR4RARBNR1H4 | |
| SCHEMBL14766879 | 0.92 | FFAR4 (0.36) | S1PR1S1PR3FFAR4GABRA1GABRB2 | |
| SCHEMBL14766285 | 0.92 | FFAR4 (0.35) | S1PR1S1PR3FFAR4GABRA1GABRB2 | |
| SCHEMBL14765828 | 0.92 | S1PR1 (0.42) | S1PR1S1PR3FFAR4RARBNR1H4 | |
| SCHEMBL14766265 | 0.92 | S1PR1 (0.40) | S1PR1S1PR3FFAR4RARBNR1H4 | |
| SCHEMBL14766154 | 0.90 | FFAR4 (0.36) | S1PR1S1PR3FFAR4RARBNR1H4 | |
| SCHEMBL12735514 | 0.90 | FFAR4 (0.37) | S1PR1S1PR3FFAR4NR1H4FFAR1 | |
| SCHEMBL14766543 | 0.89 | GABRA1 (0.36) | FFAR4GABRA1GABRB2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |