SCHEMBL14765977

SCHEMBL14765977

C=CCCOc1ccc(-c2ccc(CCc3ccc(-c4ccc(OCC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.38
FFAR1 O14842 7/20 0.37
PPARD Q03181 4/20 0.37
CNR2 P34972 2/20 0.35
FFAR4 Q5NUL3 3/20 0.33
NAAA Q02083 1/20 0.33
CNR1 P21554 1/20 0.33
GABRA1 P14867 4/20 0.33
GABRB2 P47870 4/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765991 0.94 S1PR1 (0.43) S1PR1CNR2CNR1GABRA1GABRB2
SCHEMBL14766167 0.92 CNR2 (0.36) FFAR1CNR2FFAR4CNR1GABRA1
SCHEMBL14766597 0.92 CNR2 (0.36) FFAR1CNR2FFAR4CNR1GABRA1
SCHEMBL14766003 0.92 S1PR1 (0.43) S1PR1FFAR1PPARDCNR2FFAR4
SCHEMBL14765756 0.90 FFAR1 (0.38) S1PR1FFAR1PPARDCNR2FFAR4
SCHEMBL14766604 0.90 FFAR1 (0.38) S1PR1FFAR1PPARDCNR2FFAR4
SCHEMBL14765998 0.89 FFAR1 (0.41) S1PR1FFAR1PPARDCNR2FFAR4
SCHEMBL12735667 0.89 S1PR1 (0.35) S1PR1FFAR1CNR2FFAR4CNR1
SCHEMBL14766297 0.89 FFAR1 (0.42) S1PR1FFAR1PPARDFFAR4NAAA
SCHEMBL14766638 0.88 S1PR1 (0.33) S1PR1CNR2NAAACNR1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed