Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766597 | 1.00 | CNR2 (0.36) | CNR2FFAR4FFAR1CNR1GABRA1 | |
| SCHEMBL14766470 | 0.94 | CNR2 (0.42) | CNR2CNR1GABRA1GABRB2CTSL | |
| SCHEMBL14766286 | 0.94 | CNR2 (0.42) | CNR2CNR1GABRA1GABRB2CTSL | |
| SCHEMBL14765977 | 0.92 | S1PR1 (0.38) | CNR2FFAR4FFAR1CNR1GABRA1 | |
| SCHEMBL14766600 | 0.91 | CNR2 (0.43) | CNR2CNR1GABRA1GABRB2CTSL | |
| SCHEMBL14766295 | 0.91 | CNR2 (0.43) | CNR2CNR1GABRA1GABRB2CTSL | |
| SCHEMBL14767237 | 0.89 | CTSL (0.38) | CNR2FFAR4FFAR1GABRA1GABRB2 | |
| SCHEMBL12740118 | 0.89 | FFAR4 (0.35) | CNR2FFAR4FFAR1CNR1GABRA1 | |
| SCHEMBL14766411 | 0.89 | CTSL (0.38) | CNR2FFAR4FFAR1GABRA1GABRB2 | |
| SCHEMBL12735599 | 0.89 | FFAR4 (0.35) | CNR2FFAR4FFAR1CNR1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |