Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821327 | 0.94 | KDM1A (0.42) | KDM1ANAAAHTR1ATPH1HCRTR2 | |
| SCHEMBL12736641 | 0.94 | KDM1A (0.42) | KDM1ANAAAHTR1ATPH1HCRTR2 | |
| SCHEMBL12736633 | 0.93 | KDM1A (0.41) | KDM1ANAAAHTR1ATPH1KDM5A | |
| SCHEMBL14765762 | 0.92 | KDM1A (0.50) | KDM1ANAAATPH1HCRTR2PDE4A | |
| SCHEMBL14765883 | 0.91 | KDM1A (0.40) | KDM1ANAAAHTR1APDE4AL3MBTL1 | |
| SCHEMBL12736640 | 0.91 | KDM1A (0.40) | KDM1ANAAAHTR1ATPH1HCRTR2 | |
| SCHEMBL12736634 | 0.91 | KDM1A (0.40) | KDM1ANAAAHTR1A | |
| SCHEMBL14766440 | 0.90 | NAAA (0.35) | KDM1ANAAAHTR1AHCRTR2PDE4A | |
| SCHEMBL12736637 | 0.90 | KDM1A (0.39) | KDM1ANAAAHTR1A | |
| SCHEMBL14766128 | 0.90 | KDM1A (0.36) | KDM1ANAAAHTR1APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |