Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | GYS1 | P13807 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767167 | 0.96 | FFAR1 (0.42) | FFAR1FFAR4CACNA1CPPARDHMOX1 | |
| SCHEMBL14765917 | 0.94 | S1PR1 (0.39) | FFAR1FFAR4S1PR1S1PR3GYS1 | |
| SCHEMBL12737139 | 0.92 | FFAR1 (0.39) | FFAR1FFAR4GYS1MAOBALDH2 | |
| SCHEMBL14766740 | 0.92 | S1PR1 (0.39) | FFAR1FFAR4S1PR1S1PR3GYS1 | |
| SCHEMBL14766862 | 0.89 | S1PR1 (0.38) | FFAR1FFAR4S1PR1S1PR3GYS1 | |
| SCHEMBL14766257 | 0.89 | MAOB (0.39) | FFAR1FFAR4CACNA1CPPARDHMOX1 | |
| SCHEMBL14766204 | 0.89 | FFAR1 (0.43) | FFAR1FFAR4CACNA1CPPARDHMOX1 | |
| SCHEMBL14765764 | 0.89 | S1PR1 (0.39) | FFAR1FFAR4PPARDHMOX1S1PR1 | |
| SCHEMBL12737140 | 0.88 | FFAR1 (0.39) | FFAR1FFAR4S1PR1S1PR3GYS1 | |
| SCHEMBL10302510 | 0.88 | FFAR1 (0.34) | FFAR1FFAR4PPARDS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |