Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767044 | 0.95 | MAOB (0.40) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL12737138 | 0.91 | FFAR1 (0.41) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL14766204 | 0.91 | FFAR1 (0.43) | MAOBFFAR1FFAR4NPC1RAB9A | |
| SCHEMBL14766225 | 0.89 | FFAR1 (0.41) | MAOBFFAR1FFAR4MAPTCACNA1C | |
| SCHEMBL12737127 | 0.89 | FFAR1 (0.38) | MAOBFFAR1FFAR4NPC1RAB9A | |
| SCHEMBL14766076 | 0.88 | MAOB (0.37) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL10302509 | 0.88 | MAOB (0.39) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL14766157 | 0.87 | MGAM (0.37) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL14767013 | 0.87 | MGAM (0.37) | MAOBFFAR1FFAR4MGAMGAA | |
| SCHEMBL12823432 | 0.86 | CYP2D6 (0.38) | MAOBMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |