Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767123 | 1.00 | SCN9A (0.38) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14766175 | 0.97 | SCN9A (0.38) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14766271 | 0.97 | HPGD (0.40) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14767046 | 0.97 | HPGD (0.40) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14767164 | 0.97 | SCN9A (0.38) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14922670 | 0.94 | SCN9A (0.41) | SCN9AHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL14767153 | 0.93 | HPGD (0.35) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14765999 | 0.93 | HPGD (0.35) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14766474 | 0.92 | SCN9A (0.36) | SCN9AHPGDHCRTR2RAB9ANPC1 | |
| SCHEMBL14767053 | 0.92 | SCN9A (0.36) | SCN9AHPGDHCRTR2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |