Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765999 | 1.00 | HPGD (0.35) | HPGDSCN9AHCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14767053 | 0.97 | SCN9A (0.36) | HPGDSCN9AHCRTR2ALDH1A1LSS | |
| SCHEMBL14766474 | 0.97 | SCN9A (0.36) | HPGDSCN9AHCRTR2ALDH1A1LSS | |
| SCHEMBL14766229 | 0.93 | SCN9A (0.38) | HPGDSCN9AHCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14767123 | 0.93 | SCN9A (0.38) | HPGDSCN9AHCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14766346 | 0.92 | HPGD (0.35) | HPGDSCN9AHCRTR2TSHR | |
| SCHEMBL14766278 | 0.91 | CRBN (0.35) | HPGDSCN9AHCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14766757 | 0.91 | HPGD (0.37) | HPGDSCN9AHCRTR2L3MBTL1RAB9A | |
| SCHEMBL14766729 | 0.91 | HPGD (0.37) | HPGDSCN9AHCRTR2L3MBTL1RAB9A | |
| SCHEMBL14766978 | 0.90 | FAAH (0.36) | HPGDSCN9AALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |