Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766135 | 0.98 | RARA (0.44) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14766080 | 0.97 | RARA (0.45) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14766041 | 0.93 | CNR2 (0.41) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL12736533 | 0.92 | S1PR1 (0.44) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14766147 | 0.92 | CNR2 (0.40) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14767110 | 0.92 | CYP2D6 (0.41) | RARARARBFFAR1FAAHFFAR4 | |
| SCHEMBL14765866 | 0.92 | CYP2D6 (0.41) | RARARARBFFAR1FAAHFFAR4 | |
| SCHEMBL14766642 | 0.91 | FFAR1 (0.43) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14766857 | 0.90 | FFAR1 (0.47) | RARARARBS1PR1FFAR1PPARD | |
| SCHEMBL14766172 | 0.90 | FFAR1 (0.49) | FFAR1PPARDFFAR4GSTP1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |