Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCNC | P24863 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767194 | 1.00 | MAPT (0.48) | MAPTTHRBKMT2ACCNCCDK8 | |
| SCHEMBL14766880 | 0.93 | MAPT (0.47) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL14767233 | 0.93 | MAPT (0.47) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL14766010 | 0.93 | MAPT (0.50) | MAPTTHRBKMT2ATP53NPC1 | |
| SCHEMBL12823467 | 0.93 | MAPT (0.50) | MAPTTHRBKMT2ATP53NPC1 | |
| SCHEMBL12737476 | 0.91 | MAPT (0.40) | MAPTTHRBKMT2ATP53FFAR4 | |
| SCHEMBL12742650 | 0.91 | MAPT (0.40) | MAPTTHRBKMT2ATP53FFAR4 | |
| SCHEMBL14766610 | 0.91 | MAPT (0.48) | MAPTTHRBKMT2ACCNCCDK8 | |
| SCHEMBL14766113 | 0.90 | MAPT (0.48) | MAPTTHRBKMT2ACCNCCDK8 | |
| SCHEMBL12742663 | 0.90 | S1PR1 (0.42) | MAPTTHRBKMT2ATP53FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |