Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823467 | 1.00 | MAPT (0.50) | MAPTTHRBTP53KMT2AL3MBTL1 | |
| SCHEMBL14766407 | 0.93 | MAPT (0.48) | MAPTTHRBTP53KMT2ANPC1 | |
| SCHEMBL14767194 | 0.93 | MAPT (0.48) | MAPTTHRBTP53KMT2ANPC1 | |
| SCHEMBL14766141 | 0.91 | MAPT (0.50) | MAPTTHRBTP53KMT2AL3MBTL1 | |
| SCHEMBL12823355 | 0.90 | KMT2A (0.53) | MAPTTHRBTP53KMT2AL3MBTL1 | |
| SCHEMBL12823189 | 0.90 | KMT2A (0.53) | MAPTTHRBTP53KMT2AL3MBTL1 | |
| SCHEMBL14766435 | 0.90 | MAPT (0.48) | MAPTTHRBTP53KMT2AL3MBTL1 | |
| SCHEMBL12742650 | 0.89 | MAPT (0.40) | MAPTTHRBTP53KMT2APOLB | |
| SCHEMBL12737476 | 0.89 | MAPT (0.40) | MAPTTHRBTP53KMT2APOLB | |
| SCHEMBL12822923 | 0.89 | MAPT (0.49) | MAPTTHRBTP53KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |