Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766789 | 0.97 | CRBN (0.34) | TLR4TLR2CRBNPPARGSCN9A | |
| SCHEMBL14765847 | 0.94 | TLR4 (0.33) | TLR4TLR2CRBNPPARGNPC1 | |
| SCHEMBL14766772 | 0.94 | CRBN (0.32) | TLR4TLR2CRBNPPARGNPC1 | |
| SCHEMBL14766292 | 0.92 | PPARG (0.33) | TLR4TLR2CRBNPPARG | |
| SCHEMBL14765832 | 0.91 | CRBN (0.33) | TLR4TLR2CRBNPPARGSCN9A | |
| SCHEMBL14766651 | 0.91 | PPARG (0.31) | CRBNPPARGSCN9A | |
| SCHEMBL12739117 | 0.89 | CRBN (0.35) | TLR4TLR2CRBNRAB9AACACB | |
| SCHEMBL14766092 | 0.89 | CRBN (0.31) | CRBNNPC1RAB9A | |
| SCHEMBL14766477 | 0.88 | KDM4E (0.31) | NPC1RAB9AACACB | |
| SCHEMBL12739119 | 0.87 | CRBN (0.34) | TLR4TLR2CRBNRAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |