Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765847 | 0.97 | TLR4 (0.33) | CRBNTLR4TLR2PPARGHCRTR2 | |
| SCHEMBL14766092 | 0.97 | CRBN (0.31) | CRBNHCRTR2 | |
| SCHEMBL14765687 | 0.95 | PPARG (0.32) | CRBNPPARG | |
| SCHEMBL14766789 | 0.94 | CRBN (0.34) | CRBNTLR4TLR2PPARGSCN9A | |
| SCHEMBL14765725 | 0.94 | PPARG (0.31) | CRBNPPARG | |
| SCHEMBL14766772 | 0.91 | CRBN (0.32) | CRBNTLR4TLR2PPARGSCN9A | |
| SCHEMBL14766546 | 0.91 | TLR4 (0.34) | CRBNTLR4TLR2PPARGSCN9A | |
| SCHEMBL12734168 | 0.90 | CRBN (0.34) | CRBNTLR4TLR2SCN9A | |
| SCHEMBL10301842 | 0.89 | CRBN (0.35) | CRBNTLR4TLR2PPARGSCN9A | |
| SCHEMBL14766061 | 0.89 | GPR119 (0.32) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |