SCHEMBL14766601

SCHEMBL14766601

C=CCCOc1ccc(COc2ccc(-c3ccc(C4CCC(OCCCC)CC4)c(F)c3F)cc2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.36
FFAR1 O14842 2/20 0.32
ACACA Q13085 1/20 0.32
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
HTR2A P28223 1/20 0.30
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767169 0.97 FFAR4 (0.36) FFAR4FFAR1ACACAS1PR1S1PR3
SCHEMBL14767254 0.96 FFAR4 (0.34) FFAR4FFAR1S1PR1S1PR3ALOX5AP
SCHEMBL14766246 0.95 FFAR4 (0.36) FFAR4FFAR1ACACAS1PR1S1PR3
SCHEMBL14766602 0.94 FFAR4 (0.36) FFAR4FFAR1ACACAALOX5APFEN1
SCHEMBL14766732 0.93 FFAR4 (0.34) FFAR4FFAR1S1PR1S1PR3HTR2A
SCHEMBL14766856 0.93 FFAR4 (0.40) FFAR4FFAR1ACACAS1PR1S1PR3
SCHEMBL14766154 0.93 FFAR4 (0.36) FFAR4FFAR1S1PR1S1PR3
SCHEMBL14766870 0.92 FFAR4 (0.35) FFAR4FFAR1ACACAALOX5APFEN1
SCHEMBL14766668 0.92 CRBN (0.33) FFAR1ACACAHTR2ANAAA
SCHEMBL14766879 0.91 FFAR4 (0.36) FFAR4FFAR1S1PR1S1PR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed