SCHEMBL14766870

SCHEMBL14766870

C=CCCOc1ccc(COC2CCC(c3ccc(-c4ccc(OCC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.35
FFAR1 O14842 2/20 0.35
NAAA Q02083 5/20 0.35
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
ESR1 P03372 1/20 0.30
PPARD Q03181 2/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767254 0.96 FFAR4 (0.34) FFAR4FFAR1NAAAALOX5APFEN1
SCHEMBL14766602 0.94 FFAR4 (0.36) FFAR4FFAR1NAAAALOX5APFEN1
SCHEMBL14766732 0.93 FFAR4 (0.34) FFAR4FFAR1NAAA
SCHEMBL12740371 0.93 CYP2C9 (0.34) FFAR4FFAR1NAAAALOX5APFEN1
SCHEMBL14766191 0.93 FFAR4 (0.37) FFAR4FFAR1NAAAPPARD
SCHEMBL14766601 0.92 FFAR4 (0.36) FFAR4FFAR1NAAAALOX5APFEN1
SCHEMBL14766544 0.91 NAAA (0.36) FFAR4FFAR1NAAAESR1PPARD
SCHEMBL14767021 0.91 NAAA (0.40) FFAR4FFAR1NAAAALOX5APFEN1
SCHEMBL14766606 0.90 FFAR4 (0.40) FFAR4FFAR1NAAAESR1PPARD
SCHEMBL14765684 0.90 FFAR4 (0.41) FFAR4FFAR1ALOX5APFEN1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed