Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767289 | 1.00 | MAPT (0.46) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14766535 | 0.92 | MAPT (0.44) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14766086 | 0.91 | MAPT (0.45) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14766407 | 0.90 | MAPT (0.48) | MAPTNPC1THRBKMT2ACCNC | |
| SCHEMBL14767194 | 0.90 | MAPT (0.48) | MAPTNPC1THRBKMT2ACCNC | |
| SCHEMBL14767019 | 0.90 | MAPT (0.46) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14767221 | 0.90 | MAPT (0.43) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14767313 | 0.89 | MAPT (0.42) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14766478 | 0.89 | MAPT (0.42) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL12742688 | 0.89 | KDM4E (0.39) | MAPTNPC1RAB9ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |