SCHEMBL14766623

SCHEMBL14766623

C=CCCOc1ccc(CCC2CCC(c3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.33
CRBN Q96SW2 1/20 0.32
FFAR1 O14842 1/20 0.31
HTR2A P28223 1/20 0.31
CNR1 P21554 4/20 0.30
SCN9A Q15858 1/20 0.30
SLC10A2 Q12908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766778 0.97 CNR2 (0.33) CNR2CRBNFFAR1HTR2ACNR1
SCHEMBL14765980 0.96 CNR2 (0.32) CNR2CRBN
SCHEMBL14766448 0.94 FFAR1 (0.31) FFAR1HTR2A
SCHEMBL14765911 0.93 CNR2 (0.32) CNR2CRBNSLC10A2
SCHEMBL14766754 0.93 CNR2 (0.37) CNR2CRBNFFAR1HTR2ACNR1
SCHEMBL14766668 0.90 CRBN (0.33) CNR2CRBNFFAR1HTR2ACNR1
SCHEMBL14766863 0.90 CNR2 (0.36) CNR2CRBNFFAR1HTR2ACNR1
SCHEMBL14766639 0.90 CNR2 (0.34) CNR2CRBNFFAR1HTR2ACNR1
SCHEMBL14765894 0.89 OPRL1 (0.31)
SCHEMBL14766441 0.88 SCN9A (0.31) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed