Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 6/20 | 0.33 |
| ▸ | HTR1D | P28221 | 6/20 | 0.33 |
| ▸ | HTR1B | P28222 | 6/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766639 | 0.97 | CNR2 (0.34) | CNR2CRBNCNR1HTR2AHTR1A | |
| SCHEMBL14766863 | 0.97 | CNR2 (0.36) | CNR2CRBNCNR1HTR2AHTR1A | |
| SCHEMBL14766313 | 0.95 | CNR2 (0.35) | CNR2CRBNCNR1HTR1AHTR1D | |
| SCHEMBL14766778 | 0.93 | CNR2 (0.33) | CNR2CRBNCNR1HTR2AFFAR1 | |
| SCHEMBL14766623 | 0.93 | CNR2 (0.33) | CNR2CRBNCNR1HTR2AFFAR1 | |
| SCHEMBL14765775 | 0.92 | CNR2 (0.35) | CNR2CRBNCNR1HTR1AHTR1D | |
| SCHEMBL14765923 | 0.92 | OPRL1 (0.33) | CNR2CRBNCNR1GPR119SCN9A | |
| SCHEMBL12739769 | 0.89 | CNR2 (0.38) | CNR2CRBNCNR1HTR2AFFAR1 | |
| SCHEMBL14765911 | 0.89 | CNR2 (0.32) | CNR2CRBNGPR119 | |
| SCHEMBL14765980 | 0.88 | CNR2 (0.32) | CNR2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |