SCHEMBL14766656

SCHEMBL14766656

CCCCOc1ccc(-c2ccc(CCc3ccc(C4=CCC(OCCCC)CC4)c(F)c3F)cc2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.38
NAAA Q02083 3/20 0.34
CCNT1 O60563 2/20 0.33
CDK9 P50750 2/20 0.33
RARB P10826 3/20 0.32
RARA P10276 2/20 0.32
GLA P06280 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
CNR2 P34972 1/20 0.31
RARG P13631 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766933 0.97 S1PR1 (0.38) S1PR1NAAACCNT1CDK9RARB
SCHEMBL14766715 0.97 NAAA (0.39) S1PR1NAAACCNT1CDK9RARB
SCHEMBL14766719 0.94 S1PR1 (0.35) S1PR1NAAACCNT1CDK9CNR2
SCHEMBL14766291 0.94 S1PR1 (0.35) S1PR1NAAACCNT1CDK9CNR2
SCHEMBL14766198 0.91 NAAA (0.41) S1PR1NAAACCNT1CDK9
SCHEMBL14766771 0.91 CCNT1 (0.33) CCNT1CDK9CNR2
SCHEMBL12738717 0.90 S1PR1 (0.39) S1PR1NAAACCNT1CDK9RARB
SCHEMBL14766480 0.88 CCNT1 (0.33) NAAACCNT1CDK9
SCHEMBL14766981 0.88 CCNT1 (0.33) CCNT1CDK9
SCHEMBL14766634 0.87 S1PR1 (0.41) S1PR1CCNT1CDK9RARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed