SCHEMBL14766741

SCHEMBL14766741

CCCCOC1CCC(c2ccc(-c3ccc(OCc4ccc(OCC)c(F)c4F)cc3)c(F)c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.38
NAAA Q02083 1/20 0.33
ESR1 P03372 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
RET P07949 1/20 0.30
FPR2 P25090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766193 1.00 FFAR4 (0.38) FFAR4NAAAESR1CHRM2CHRM4
SCHEMBL14766488 0.97 FFAR4 (0.39) FFAR4NAAAESR1CHRM2CHRM4
SCHEMBL14766614 0.97 FFAR4 (0.39) FFAR4NAAAESR1CHRM2CHRM4
SCHEMBL14766256 0.94 FFAR4 (0.38) FFAR4ESR1CHRM2CHRM4CHRM5
SCHEMBL14766993 0.94 FFAR4 (0.38) FFAR4ESR1CHRM2CHRM4CHRM5
SCHEMBL14766582 0.94 NAAA (0.36) FFAR4NAAAESR1CHRM2CHRM4
SCHEMBL14766099 0.94 NAAA (0.36) FFAR4NAAAESR1CHRM2CHRM4
SCHEMBL14766735 0.92 FFAR4 (0.38) FFAR4NAAAESR1ALOX5APFEN1
SCHEMBL14766520 0.92 FFAR4 (0.38) FFAR4NAAAESR1ALOX5APFEN1
SCHEMBL14765890 0.91 FFAR4 (0.36) FFAR4NAAAESR1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed