Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | CPS1 | P31327 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767028 | 0.93 | FFAR4 (0.37) | FFAR4FFAR1CAMKK1CAMKK2NPC1 | |
| SCHEMBL12737908 | 0.93 | FFAR4 (0.34) | FFAR4FFAR1CAMKK1CAMKK2MAPT | |
| SCHEMBL14766060 | 0.93 | FFAR4 (0.43) | FFAR4FFAR1CAMKK1CAMKK2CPS1 | |
| SCHEMBL14766386 | 0.92 | FFAR4 (0.41) | FFAR4FFAR1CAMKK1CAMKK2CPS1 | |
| SCHEMBL12737867 | 0.91 | FFAR4 (0.37) | FFAR4FFAR1CAMKK1CAMKK2CPS1 | |
| SCHEMBL12822764 | 0.90 | APP (0.34) | FFAR4FFAR1CAMKK1CAMKK2MAPT | |
| SCHEMBL14767303 | 0.89 | MEN1 (0.35) | FFAR4FFAR1CAMKK1CAMKK2NPC1 | |
| SCHEMBL14766454 | 0.89 | MEN1 (0.35) | FFAR4FFAR1CAMKK1CAMKK2NPC1 | |
| SCHEMBL14766505 | 0.89 | FFAR4 (0.46) | FFAR4FFAR1CAMKK1CAMKK2CPS1 | |
| SCHEMBL12737859 | 0.89 | FFAR4 (0.39) | FFAR4FFAR1CAMKK1CAMKK2CPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |