SCHEMBL14766386

SCHEMBL14766386

C=CCCOc1ccc(C2CCC(OC(=O)c3ccc(-c4ccc(OCC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.41
FFAR1 O14842 2/20 0.41
CAMKK1 Q8N5S9 2/20 0.35
CAMKK2 Q96RR4 2/20 0.35
PPARD Q03181 1/20 0.34
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
CRBN Q96SW2 1/20 0.33
CPS1 P31327 2/20 0.33
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
DHODH Q02127 1/20 0.32
PRKAB2 O43741 1/20 0.32
PRKAG1 P54619 1/20 0.32
PRKAA2 P54646 1/20 0.32
PRKAA1 Q13131 1/20 0.32
PRKAG3 Q9UGI9 1/20 0.32
PRKAG2 Q9UGJ0 1/20 0.32
PRKAB1 Q9Y478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766667 0.96 FFAR4 (0.39) FFAR4FFAR1CAMKK1CAMKK2RARA
SCHEMBL12737913 0.93 FFAR4 (0.35) FFAR4FFAR1CAMKK1CAMKK2CRBN
SCHEMBL14766250 0.93 FFAR4 (0.39) FFAR4FFAR1CAMKK1CAMKK2PPARD
SCHEMBL14767232 0.93 FFAR4 (0.39) FFAR4FFAR1CAMKK1CAMKK2PPARD
SCHEMBL14766830 0.92 FFAR4 (0.38) FFAR4FFAR1CAMKK1CAMKK2CPS1
SCHEMBL14766060 0.91 FFAR4 (0.43) FFAR4FFAR1CAMKK1CAMKK2PPARD
SCHEMBL14766505 0.91 FFAR4 (0.46) FFAR4FFAR1CAMKK1CAMKK2PPARD
SCHEMBL12823126 0.91 FFAR4 (0.34) FFAR4FFAR1
SCHEMBL12737915 0.90 FFAR4 (0.37) FFAR4FFAR1PPARDRARARARB
SCHEMBL14766858 0.89 RARA (0.40) FFAR4FFAR1PPARDRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed