Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12738833 | 0.91 | FFAR4 (0.37) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL14766758 | 0.90 | CTSL (0.36) | FFAR4FGFR2FGFR1CTSLCTSS | |
| SCHEMBL1243473 | 0.90 | FFAR4 (0.40) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL14766725 | 0.89 | CNR2 (0.35) | FFAR4S1PR1S1PR3CTSLCTSS | |
| SCHEMBL12738845 | 0.87 | FFAR4 (0.39) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL10301919 | 0.86 | FFAR4 (0.40) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL10301920 | 0.86 | CTSL (0.44) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL12740092 | 0.86 | CTSL (0.41) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL12717240 | 0.86 | FFAR4 (0.39) | FFAR4FGFR2FGFR1S1PR1S1PR3 | |
| SCHEMBL12740090 | 0.86 | FFAR4 (0.39) | FFAR4FGFR2FGFR1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |