SCHEMBL14766900

SCHEMBL14766900

CCOc1ccc(COC2CCC(c3ccc(C4CCC(OCC)CC4)c(F)c3F)CC2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
HTR1A P08908 1/20 0.35
HCRTR2 O43614 3/20 0.32
CCR5 P51681 1/20 0.32
KDM1A O60341 2/20 0.32
ACACB O00763 2/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
MAPT P10636 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765825 1.00 NAAA (0.39) NAAAHTR1AHCRTR2CCR5KDM1A
SCHEMBL14922552 0.97 NAAA (0.40) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL14922636 0.94 NAAA (0.37) NAAAHTR1AHCRTR2ACACBL3MBTL1
SCHEMBL15381649 0.94 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL15381759 0.94 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL10302578 0.94 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL14922547 0.93 NAAA (0.36) NAAAHTR1AHCRTR2L3MBTL1
SCHEMBL12736607 0.93 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL12718957 0.93 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB
SCHEMBL12823196 0.93 NAAA (0.38) NAAAHTR1AHCRTR2KDM1AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed