SCHEMBL14766964

SCHEMBL14766964

CCCCOC1CCC(c2ccc(-c3ccc(COc4ccc(OCC)c(F)c4)cc3)c(F)c2F)CC1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.39
PPARD Q03181 13/20 0.39
NAAA Q02083 2/20 0.36
FFAR4 Q5NUL3 1/20 0.35
F10 P00742 1/20 0.35
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767111 0.97 FFAR1 (0.38) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14766765 0.96 FFAR1 (0.39) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14766617 0.95 FFAR1 (0.37) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14767037 0.95 FFAR1 (0.38) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14766567 0.95 PPARD (0.39) FFAR1PPARDNAAAFFAR4PPARA
SCHEMBL14766959 0.93 FFAR1 (0.38) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14767016 0.93 FFAR1 (0.41) FFAR1PPARDNAAAF10PPARA
SCHEMBL14767003 0.92 PPARD (0.38) FFAR1PPARDNAAAFFAR4PPARA
SCHEMBL14766960 0.92 GABRA1 (0.35) FFAR1PPARDNAAAFFAR4F10
SCHEMBL14767224 0.91 GABRA1 (0.35) FFAR1PPARDNAAAFFAR4F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed