Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766769 | 0.95 | HPGD (0.35) | POLBTSHRMAPK1HPGDMTNR1A | |
| SCHEMBL14767260 | 0.93 | POLB (0.35) | POLBTSHRMAPK1HPGDMTNR1A | |
| SCHEMBL14767172 | 0.91 | HPGD (0.35) | POLBTSHRMAPK1HPGDHCRTR2 | |
| SCHEMBL14767305 | 0.91 | HPGD (0.39) | HPGDMTNR1AHCRTR2PPARDFFAR1 | |
| SCHEMBL12742206 | 0.90 | POLB (0.40) | POLBTSHRMAPK1HPGDMTNR1A | |
| SCHEMBL14767258 | 0.89 | HPGD (0.37) | POLBTSHRMAPK1HPGDHCRTR2 | |
| SCHEMBL14766329 | 0.89 | HPGD (0.37) | POLBTSHRMAPK1HPGDHCRTR2 | |
| SCHEMBL14766343 | 0.88 | HPGD (0.37) | POLBTSHRMAPK1HPGDHCRTR2 | |
| SCHEMBL14767156 | 0.87 | FFAR1 (0.37) | POLBTSHRMAPK1HPGDMTNR1A | |
| SCHEMBL14766421 | 0.87 | HPGD (0.35) | HPGDHCRTR2PPARDSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |