Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 8/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766329 | 1.00 | HPGD (0.37) | HPGDKDM4EHTR2CHTR2BHCRTR2 | |
| SCHEMBL14766729 | 0.91 | HPGD (0.37) | HPGDKDM4EHCRTR2KMT2AMEN1 | |
| SCHEMBL14766757 | 0.91 | HPGD (0.37) | HPGDKDM4EHCRTR2KMT2AMEN1 | |
| SCHEMBL14766343 | 0.91 | HPGD (0.37) | HPGDKDM4EHTR2CHTR2BHCRTR2 | |
| SCHEMBL14766769 | 0.90 | HPGD (0.35) | HPGDKDM4EHTR2CHTR2BHCRTR2 | |
| SCHEMBL12742066 | 0.90 | HPGD (0.36) | HPGDKDM4EHTR2CHTR2BPOLB | |
| SCHEMBL12737172 | 0.90 | HPGD (0.36) | HPGDKDM4EHTR2CHTR2BPOLB | |
| SCHEMBL14766044 | 0.89 | HPGD (0.43) | HPGDHCRTR2POLBKMT2AMEN1 | |
| SCHEMBL14767287 | 0.89 | HPGD (0.43) | HPGDHCRTR2POLBKMT2AMEN1 | |
| SCHEMBL14766980 | 0.89 | POLB (0.39) | HPGDKDM4EHTR2CHTR2BHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |