Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SI | P14410 | 4/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766157 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL12737044 | 0.92 | FFAR1 (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL12740502 | 0.92 | FFAR1 (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14766202 | 0.91 | FFAR1 (0.42) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL10302456 | 0.91 | MGAM (0.36) | MGAMGAASIMGAM2FFAR1 | |
| SCHEMBL14766253 | 0.89 | FFAR1 (0.41) | MAPTNPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL14767163 | 0.89 | FFAR1 (0.41) | MAPTNPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL14766117 | 0.88 | FFAR1 (0.35) | MAPTNPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL14766621 | 0.88 | FFAR1 (0.35) | MAPTNPC1RAB9AFFAR1FFAR4 | |
| SCHEMBL10303263 | 0.88 | CYP2D6 (0.36) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |