Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767163 | 1.00 | FFAR1 (0.41) | FFAR1FFAR4CACNA1CNQO1TDP1 | |
| SCHEMBL10302498 | 0.94 | FFAR1 (0.39) | FFAR1FFAR4CACNA1CNQO1TDP1 | |
| SCHEMBL12737020 | 0.93 | FFAR1 (0.43) | FFAR1FFAR4CACNA1CTDP1CYP1A2 | |
| SCHEMBL12740490 | 0.93 | FFAR1 (0.43) | FFAR1FFAR4CACNA1CTDP1CYP1A2 | |
| SCHEMBL13586554 | 0.93 | LMNA (0.39) | FFAR1FFAR4L3MBTL1MAPTKDM4E | |
| SCHEMBL12823203 | 0.93 | LMNA (0.39) | FFAR1FFAR4L3MBTL1MAPTKDM4E | |
| SCHEMBL10302449 | 0.93 | FFAR1 (0.39) | FFAR1FFAR4CACNA1CTDP1CYP1A2 | |
| SCHEMBL10303168 | 0.93 | GYS1 (0.39) | FFAR1FFAR4CACNA1CMAPTNPC1 | |
| SCHEMBL12740480 | 0.92 | FFAR4 (0.40) | FFAR1FFAR4CACNA1CTDP1CYP1A2 | |
| SCHEMBL14766627 | 0.92 | CYP2D6 (0.40) | FFAR1FFAR4CACNA1CTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |