Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717009 | 1.00 | DAO (0.34) | DAOOPRL1DRD2HTR2ADRD3 | |
| SCHEMBL1242547 | 0.94 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL1242548 | 0.94 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL14922530 | 0.94 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL10303044 | 0.92 | KCNH2 (0.34) | HTR2A | |
| SCHEMBL14765907 | 0.91 | HCRTR2 (0.31) | OPRL1 | |
| SCHEMBL14766388 | 0.91 | HCRTR2 (0.31) | OPRL1 | |
| SCHEMBL10302054 | 0.91 | CTSL (0.34) | OPRL1 | |
| SCHEMBL12734848 | 0.91 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL12739661 | 0.91 | OPRL1 (0.31) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |