Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766328 | 0.95 | OPRL1 (0.35) | OPRL1CHRNB2CHRNA4FFAR1GPR119 | |
| SCHEMBL14766639 | 0.92 | CNR2 (0.34) | HTR2AHTR2COPRL1FFAR1GPR119 | |
| SCHEMBL12718746 | 0.91 | DAO (0.36) | HTR2AHTR2COPRL1FFAR1MEN1 | |
| SCHEMBL12739759 | 0.91 | HTR2A (0.35) | HTR2AHTR2COPRL1CHRNB2CHRNA4 | |
| SCHEMBL12739757 | 0.91 | HTR2A (0.35) | HTR2AHTR2COPRL1CHRNB2CHRNA4 | |
| SCHEMBL12739768 | 0.90 | HTR2A (0.34) | HTR2AHTR2COPRL1CHRNB2CHRNA4 | |
| SCHEMBL14766966 | 0.90 | HTR2A (0.33) | HTR2AHTR2CMEN1KMT2AMTNR1A | |
| SCHEMBL12739767 | 0.89 | FFAR1 (0.35) | HTR2AHTR2CFFAR1ACACAMEN1 | |
| SCHEMBL14766754 | 0.88 | CNR2 (0.37) | HTR2AHTR2CFFAR1GPR119 | |
| SCHEMBL14766448 | 0.88 | FFAR1 (0.31) | HTR2AHTR2CFFAR1ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |