Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 5/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766009 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2CNR2CNR1FEN1 | |
| SCHEMBL14766036 | 0.97 | GABRA1 (0.36) | GABRA1GABRB2CNR2CNR1FEN1 | |
| SCHEMBL14767059 | 0.97 | GABRA1 (0.36) | GABRA1GABRB2CNR2CNR1FEN1 | |
| SCHEMBL14766755 | 0.94 | GABRA1 (0.36) | GABRA1GABRB2FEN1ALOX5APHTR1A | |
| SCHEMBL14766004 | 0.94 | GABRA1 (0.36) | GABRA1GABRB2FEN1ALOX5APHTR1A | |
| SCHEMBL14766616 | 0.93 | FEN1 (0.35) | FEN1ALOX5APHTR1ASLC6A2SLC6A4 | |
| SCHEMBL14765826 | 0.93 | FEN1 (0.35) | FEN1ALOX5APHTR1ASLC6A2SLC6A4 | |
| SCHEMBL14767295 | 0.92 | FFAR1 (0.33) | GABRA1GABRB2CNR2CNR1NAAA | |
| SCHEMBL14767224 | 0.92 | GABRA1 (0.35) | GABRA1GABRB2CNR2CNR1NAAA | |
| SCHEMBL14766042 | 0.91 | S1PR1 (0.35) | GABRA1GABRB2CNR2CNR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |