Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LIPC | P11150 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766263 | 1.00 | SCN9A (0.36) | SCN9ALSSGRM2CNR1CNR2 | |
| SCHEMBL14767039 | 0.97 | SCN9A (0.37) | SCN9ALSSGRM2CNR1CNR2 | |
| SCHEMBL14766901 | 0.97 | SCN9A (0.37) | SCN9ALSSGRM2CNR1CNR2 | |
| SCHEMBL14766323 | 0.93 | SCN9A (0.40) | SCN9AGRM2CNR1CNR2ALDH1A1 | |
| SCHEMBL14767196 | 0.93 | SCN9A (0.40) | SCN9AGRM2CNR1CNR2ALDH1A1 | |
| SCHEMBL14766131 | 0.92 | SCN9A (0.36) | SCN9ACRBN | |
| SCHEMBL14766864 | 0.91 | KDM4E (0.37) | SCN9AGRM2HRH2KDM4E | |
| SCHEMBL14766626 | 0.91 | KDM4E (0.37) | SCN9AGRM2HRH2KDM4E | |
| SCHEMBL14767242 | 0.91 | SCN9A (0.39) | SCN9AGRM2CNR1CNR2ALDH1A1 | |
| SCHEMBL14767067 | 0.91 | SCN9A (0.37) | SCN9AGRM2CNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |