Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766626 | 1.00 | KDM4E (0.37) | KDM4ESCN9AACACBGRM2NTSR1 | |
| SCHEMBL14766901 | 0.94 | SCN9A (0.37) | KDM4ESCN9AACACBGRM2NTSR1 | |
| SCHEMBL14767039 | 0.94 | SCN9A (0.37) | KDM4ESCN9AACACBGRM2NTSR1 | |
| SCHEMBL12741084 | 0.92 | KDM4E (0.37) | KDM4ESCN9AGRM2 | |
| SCHEMBL12737615 | 0.92 | KDM4E (0.37) | KDM4ESCN9AGRM2 | |
| SCHEMBL14766529 | 0.91 | TPH1 (0.33) | KDM4ESCN9AHCRTR2 | |
| SCHEMBL14766431 | 0.91 | HTR2C (0.33) | KDM4EACACBHCRTR2MAPTSMN1; SMN2 | |
| SCHEMBL14767109 | 0.91 | HTR2C (0.33) | KDM4EACACBHCRTR2MAPTSMN1; SMN2 | |
| SCHEMBL14767166 | 0.91 | SCN9A (0.36) | KDM4ESCN9AGRM2HRH2 | |
| SCHEMBL14766263 | 0.91 | SCN9A (0.36) | KDM4ESCN9AGRM2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |