Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 11/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178662 | 0.92 | TTK (0.48) | TTKZAP70KARS1ADORA3FYN | |
| SCHEMBL14767505 | 0.90 | ADORA3 (0.46) | TTKADORA3FYNPDE10A | |
| SCHEMBL2182480 | 0.86 | ZAP70 (0.46) | TTKZAP70KARS1FYN | |
| SCHEMBL14767524 | 0.86 | TTK (0.43) | TTKZAP70KARS1FYN | |
| SCHEMBL12409298 | 0.82 | MAPK1 (0.48) | TTKADORA3FYNPDE10A | |
| SCHEMBL12409242 | 0.82 | TTK (0.56) | TTKADORA3FYN | |
| SCHEMBL2179881 | 0.81 | CFTR (0.54) | TTKZAP70KARS1ADORA3FYN | |
| SCHEMBL2178112 | 0.81 | TTK (0.56) | TTKZAP70KARS1FYN | |
| SCHEMBL3469243 | 0.81 | ADORA3 (0.51) | TTKZAP70KARS1ADORA3FYN | |
| SCHEMBL14668744 | 0.81 | FYN (0.51) | TTKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567960-A2 | Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis | Biofocus DPI Limited (GB) | 2013-03-13 | — | — | EP | disclosed |