SCHEMBL14767680

SCHEMBL14767680

COc1ccc(OC(=O)c2ccccc2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 12/20 0.57
MAPT P10636 5/20 0.57
TDP1 Q9NUW8 3/20 0.57
MEN1 O00255 3/20 0.57
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52
NPBWR1 P48145 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
CYP3A4 P08684 1/20 0.50
PKM P14618 1/20 0.50
PARP10 Q53GL7 1/20 0.49
HSD17B10 Q99714 1/20 0.48
CA12 O43570 1/20 0.47
POLB P06746 1/20 0.47
CA9 Q16790 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16021865 0.90 KMT2A (0.60) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL16429577 0.90 KMT2A (0.56) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL10436239 0.87 KMT2A (0.60) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL10910755 0.84 KMT2A (0.57) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL4581548 0.84 CYP1A2 (0.63) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL14641551 0.84 KMT2A (0.53) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL11072007 0.83 KMT2A (0.64) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL13657591 0.83 MAPT (0.56) KMT2AMAPTTDP1MEN1L3MBTL1
SCHEMBL10042169 0.83 KMT2A (0.61) KMT2AMAPTALDH1A1GAAL3MBTL1
SCHEMBL17301223 0.82 MAPT (0.51) KMT2AMAPTTDP1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1793246-B1 POLYMERIC OPTICAL RETARDATION FILM INFILTRATED WITH ANISOTROPIC LIQUID CRYSTAL MATERIAL, OPTICAL FUNCTIONAL FILM, POLARIZING FILM AND DISPLAY APPARATUS DAINIPPON PRINTING CO LTD (JP) 2013-03-13 EP disclosed