Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258677 | 0.87 | DHFR (0.47) | DHFRDCPSMCHR1BRD4P2RX4 | |
| SCHEMBL10257341 | 0.81 | MCHR1 (0.51) | DHFRDCPSMCHR1BRD4GRM4 | |
| SCHEMBL2416840 | 0.79 | MCHR1 (0.40) | DHFRDCPSMCHR1BRD4 | |
| SCHEMBL2419230 | 0.77 | MCHR1 (0.46) | DHFRDCPSMCHR1BRD4 | |
| SCHEMBL27102256 | 0.76 | MCHR1 (0.47) | MCHR1 | |
| SCHEMBL10266648 | 0.75 | BRD4 (0.35) | DHFRDCPSMCHR1BRD4P2RX4 | |
| SCHEMBL6015806 | 0.75 | IKBKB (0.41) | MCHR1PIM1PIM2 | |
| SCHEMBL10258266 | 0.72 | BRD4 (0.42) | BRD4FFAR2 | |
| SCHEMBL620797 | 0.71 | KAT2B (0.38) | DHFRDCPSMCHR1PIM1PIM3 | |
| SCHEMBL15605503 | 0.71 | IRAK4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |