SCHEMBL14767705

SCHEMBL14767705

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nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.32
MGAM O43451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18390975 1.00 TDP1 (0.36) TDP1TSHRMGAM
SCHEMBL14290032 1.00 TDP1 (0.36) TDP1TSHRMGAM
SCHEMBL14407114 1.00 TDP1 (0.36) TDP1TSHRMGAM
SCHEMBL19352766 0.92 TDP1 (0.38) TDP1TSHRMGAM
SCHEMBL14145061 0.92 TDP1 (0.38) TDP1TSHRMGAM
SCHEMBL14185806 0.92 TDP1 (0.38) TDP1TSHRMGAM
SCHEMBL20805074 0.92 TDP1 (0.38) TDP1TSHRMGAM
SCHEMBL7256974 0.89 TDP1 (0.37) TDP1TSHRMGAM
SCHEMBL4941872 0.89 TDP1 (0.37) TDP1TSHRMGAM
SCHEMBL26018904 0.83 TDP1 (0.35) TDP1TSHRMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280983-B1 C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY TFCHEM (FR) 2013-03-13 EP disclosed