Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256974 | 1.00 | TDP1 (0.37) | TDP1MGAMLMNAL3MBTL1TSHR | |
| SCHEMBL11147863 | 0.89 | LMNA (0.55) | TDP1MGAMLMNAL3MBTL1 | |
| SCHEMBL12831105 | 0.89 | LMNA (0.55) | TDP1MGAMLMNAL3MBTL1 | |
| SCHEMBL18390975 | 0.89 | TDP1 (0.36) | TDP1MGAMTSHR | |
| SCHEMBL14767705 | 0.89 | TDP1 (0.36) | TDP1MGAMTSHR | |
| SCHEMBL14290032 | 0.89 | TDP1 (0.36) | TDP1MGAMTSHR | |
| SCHEMBL14407114 | 0.89 | TDP1 (0.36) | TDP1MGAMTSHR | |
| SCHEMBL19741237 | 0.89 | LMNA (0.55) | TDP1MGAMLMNAL3MBTL1 | |
| SCHEMBL19741235 | 0.89 | LMNA (0.55) | TDP1MGAMLMNAL3MBTL1 | |
| SCHEMBL18652682 | 0.89 | MGAM (0.32) | TDP1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262249-A1 | Psorospermin and Analogues | CYLENE PHARMACEUTICALS, INC. | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262249-A1 | Psorospermin and Analogues | BPGM, SUCLG2, MTPN | TDP1 2275/4885MGAM 1463/4885LMNA 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.