SCHEMBL14767830

SCHEMBL14767830

C1=CC[C@H]2NCCNC2C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14759902 1.00 L3MBTL1 (0.32) L3MBTL1
SCHEMBL3357588 0.76
SCHEMBL3357586 0.76
SCHEMBL3357590 0.76
SCHEMBL5939656 0.72 EPAS1 (0.38)
SCHEMBL5939649 0.72 EPAS1 (0.38)
SCHEMBL5939367 0.72 EPAS1 (0.38)
SCHEMBL5939379 0.72 EPAS1 (0.38)
SCHEMBL942888 0.69 L3MBTL1 (0.37) L3MBTL1
SCHEMBL6156594 0.67 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2567959-A1 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors SANOFI (FR) 2013-03-13 EP disclosed