Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | TDP2 | O95551 | 2/20 | 0.30 |
| ▸ | CASP3 | P42574 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799595 | 0.75 | HTR2A (0.48) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL14767895 | 0.69 | HTR2A (0.34) | — | |
| Hydrochloric Acid SCHEMBL7609388 | 0.66 | HTR2A (0.42) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5669994 | 0.66 | HTR2A (0.45) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3640617 | 0.65 | CES2 (0.39) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL9161284 | 0.65 | HTR2A (0.44) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL20313205 | 0.64 | HPGD (0.64) | HPGDAPPMEN1KMT2AMAPT | |
| SCHEMBL22347020 | 0.64 | HTR2A (0.50) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL12958033 | 0.63 | HPGD (0.86) | HPGDMEN1KMT2AMAPTHTT | |
| SCHEMBL401617 | 0.63 | HPGD (0.77) | HPGDMEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542962-B1 | Monoaminofluorene compound and organic light-emitting device using the same | CANON KK (JP) | 2013-03-13 | — | — | EP | disclosed |