Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424079 | 1.00 | CYP2C19 (0.52) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL26119692 | 0.84 | CYP2C9 (0.54) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL13400274 | 0.84 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL392804 | 0.83 | SMN1; SMN2 (0.52) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL2244019 | 0.83 | CYP2C19 (0.52) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL30448978 | 0.83 | SMN1; SMN2 (0.52) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL10707367 | 0.83 | SMN1; SMN2 (0.52) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL396132 | 0.82 | CYP2C9 (0.45) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL11341071 | 0.82 | CYP2C19 (0.56) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL30615138 | 0.81 | SMN1; SMN2 (0.45) | CYP2C19CYP2C9CYP1A2CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814688-B2 | Markers for determining tumor hypoxia | VIB VZW (BE) | 2023-11-14 | — | — | US | disclosed |
| US-20220259677-A1 | Markers for Determining Tumor Hypoxia | VIB VZW (BE) | 2022-08-18 | — | — | US | disclosed |
| EP-3265582-B1 | MARKERS FOR DETERMINING TUMOR HYPOXIA | VIB VZW (BE) | 2021-07-28 | — | — | EP | disclosed |
| US-20180051345-A1 | Markers for Determining Tumor Hypoxia | VIB VZW (BE) | 2018-02-22 | — | — | US | disclosed |
| EP-3265582-A1 | MARKERS FOR DETERMINING TUMOR HYPOXIA | VIB vzw (BE) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016142295-A1 | MARKERS FOR DETERMINING TUMOR HYPOXIA | VIB VZW (BE) | 2016-09-15 | — | — | WO | disclosed |
| US-8673818-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8334300-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSHAFT (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20120305148-A1 | MALLEABLE SOLID EXPLOSIVE AND METHOD FOR OBTAINING IT | EURENCO (FR) | 2012-12-06 | — | — | US | disclosed |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-20030216260-A1 | C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| EP-1280770-A1 | C 2? PHENYL-SUBSTITUTED CYCLIC KETO-ENOLS USED AS PESTICIDES AND HERBICIDES | Bayer Aktiengesellschaft (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001074770-A1 | C2 PHENYL-SUBSTITUTED CYCLIC KETO-ENOLS USED AS PESTICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2001-10-11 | — | — | WO | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |
| EP-0407901-B1 | PROCESS FOR THE FABRICATION OF POLYETHYLENE FIBRES BY THE HIGH SPEED SPINNING OF ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE | AKZO N.V. (NL) | 1993-01-13 | — | — | EP | disclosed |
| US-5068073-A | Method of manufacturing polyethylene fibers by high speed spinning of ultra-high-molecular-weight polyethylene | AKZO N.V. (NL) | 1991-11-26 | — | — | US | disclosed |
| EP-0407901-A2 | Process for the fabrication of polyethylene fibres by the high speed spinning of ultra-high molecular weight polyethylene | AKZO N.V. (NL) | 1991-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216260-A1 | C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides | PDHX, AKR1C3, AKR1A1 | CYP2C19 352/4885CYP2C9 193/4885CYP1A2 81/4885 |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, AKR1C4, AKR1C2 | CYP2C19 355/4885CYP2C9 304/4885CYP1A2 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.