Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288029 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1SYKSMN1; SMN2 | |
| SCHEMBL29415387 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1SYKSMN1; SMN2 | |
| SCHEMBL25250386 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1SYKSMN1; SMN2 | |
| SCHEMBL12439801 | 0.80 | SYK (0.41) | ALDH1A1MAPK1L3MBTL1SYKPPARA | |
| SCHEMBL418232 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SYKSMN1; SMN2 | |
| SCHEMBL1149587 | 0.79 | SYK (0.40) | ALDH1A1MAPK1L3MBTL1SYKPPARA | |
| SCHEMBL2138671 | 0.78 | SYK (0.46) | ALDH1A1MAPK1L3MBTL1SYKPPARA | |
| SCHEMBL2137495 | 0.78 | SYK (0.46) | ALDH1A1MAPK1L3MBTL1SYKPPARA | |
| SCHEMBL14439276 | 0.78 | SYK (0.39) | ALDH1A1MAPK1L3MBTL1SYKPPARA | |
| SCHEMBL8046788 | 0.78 | SYK (0.39) | ALDH1A1MAPK1L3MBTL1SYKPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439986-B2 | Tricarbonyl technetium-99m, rhenium-185/187, or rhenium-188 labeled cyclic RGD derivatives and uses thereof | BIO IMAGING KOREA CO., LTD. (KR) | 2016-09-13 | — | — | US | disclosed |
| US-20130064766-A1 | TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES | SNU R&DB FOUNDATION (KR) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064766-A1 | TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES | ITGAV, ITGA5, KDR | ALDH1A1 4074/4885MAPK1 2911/4885L3MBTL1 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.