SCHEMBL14768516

SCHEMBL14768516

CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
IDO1 P14902 1/20 0.56
SYK P43405 1/20 0.51
BCHE P06276 2/20 0.48
CNR2 P34972 2/20 0.48
L3MBTL1 Q9Y468 3/20 0.46
TLR2 O60603 1/20 0.46
TLR1 Q15399 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 1/20 0.43
CTSS P25774 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26689306 1.00 LMNA (0.61) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL26689707 1.00 LMNA (0.61) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL24983406 0.99 SMN1; SMN2 (0.63) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL29467616 0.97 LMNA (0.57) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL29467724 0.96 LMNA (0.56) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL20107353 0.91 LMNA (0.61) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL18886286 0.91 SMN1; SMN2 (0.69) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL24572425 0.91 SMN1; SMN2 (0.69) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL12196470 0.90 SMN1; SMN2 (0.76) LMNASMN1; SMN2IDO1SYKBCHE
SCHEMBL1668653 0.89 SMN1; SMN2 (0.71) LMNASMN1; SMN2IDO1SYKL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651903-A1 M6PR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP disclosed
WO-2024239281-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO disclosed
WO-2024155748-A1 M6PR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
US-9439986-B2 Tricarbonyl technetium-99m, rhenium-185/187, or rhenium-188 labeled cyclic RGD derivatives and uses thereof BIO IMAGING KOREA CO., LTD. (KR) 2016-09-13 US disclosed
US-9439986-B2 Tricarbonyl technetium-99m, rhenium-185/187, or rhenium-188 labeled cyclic RGD derivatives and uses thereof BIO IMAGING KOREA CO., LTD. (KR) 2016-09-13 US disclosed
EP-2583966-B1 TRICARBONYL TECHNETIUM-99M OR RHENIUM-188 LABEL RING RGD DERIVATIVE, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES BIO IMAGING KOREA CO LTD (KR) 2016-08-10 EP disclosed
EP-2583966-A2 TRICARBONYL TECHNETIUM-99M OR RHENIUM-188 LABEL RING RGD DERIVATIVE, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES SNU R & DB Foundation (KR) 2013-04-24 EP disclosed
US-20130064766-A1 TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES SNU R&DB FOUNDATION (KR) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130064766-A1 TRICARBONYL TECHNETIUM-99m OR RHENIUM-188 LABELED CYCLIC RGD DERIVATIVES, A PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES AS AN ACTIVE INGREDIENT FOR USE IN THE DIAGNOSIS OR TREATMENT OF ANGIOGENESIS-RELATED DISEASES ITGAV, ITGA5, KDR LMNA 1763/4885SMN1; SMN2 3984/4885IDO1 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.