Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286903 | 0.85 | CARM1 (0.40) | GBA1KDM1AL3MBTL1KCNH2 | |
| SCHEMBL14488004 | 0.81 | L3MBTL1 (0.49) | KDM1AL3MBTL1KCNH2 | |
| SCHEMBL20888184 | 0.77 | GBA1 (0.46) | GBA1HSD11B1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL14751750 | 0.77 | GBA1 (0.46) | GBA1HSD11B1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL25144481 | 0.77 | GBA1 (0.37) | GBA1L3MBTL1 | |
| SCHEMBL25387761 | 0.77 | GBA1 (0.41) | GBA1KDM1AHSD11B1CYP2D6KCNH2 | |
| SCHEMBL23598176 | 0.76 | GBA1 (0.42) | GBA1KDM1AHSD11B1CYP2D6SLC6A2 | |
| SCHEMBL19080606 | 0.75 | L3MBTL1 (0.33) | GBA1L3MBTL1 | |
| SCHEMBL20888183 | 0.75 | GBA1 (0.44) | GBA1HSD11B1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL14768541 | 0.75 | GBA1 (0.44) | GBA1HSD11B1CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036665-A1 | COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | SATORI PHARMACEUTICALS, INC. (US) | 2013-03-14 | — | — | WO | disclosed |
| WO-2013036669-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2013-03-14 | — | — | WO | disclosed |